Molecular biology
Nucleic acid analogues are used in molecular biology for several purposes:
- As a tool to detect particular sequences
- As a tool with resistance to RNA hydrolysis)
- As a tool for another purpose, such as sequencing
- Naturally occurring, such as in tRNA
- Investigation of the mechanisms used by enzyme, such as an Enzyme inhibitor)
- Investigation of possible scenarios of the origin of life
- Investigation of the structural features of nucleic acids
- Investigation of the possible alternatives to the natural system in Synthetic biology

Common changes in nucleotide analogues